Synthetic Route of 106092-11-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 106092-11-9, Name is (R)-4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine, molecular formula is C7H11N3S. In a Article，once mentioned of 106092-11-9
Development of novel DNA gyrase B inhibitors is an important field of antibacterial drug discovery whose aim is to introduce a more effective representative of this mechanistic class into the clinic. In the present study, two new series of Escherichia coli DNA gyrase inhibitors bearing the 4,5-dibromopyrrolamide moiety have been designed and synthesized. 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole-2,6-diamine derivatives inhibited E. coli DNA gyrase in the submicromolar to low micromolar range (IC50values between 0.891 and 10.4 muM). Their ?ring-opened? analogues, based on the 2-(2-aminothiazol-4-yl)acetic acid scaffold, displayed weaker DNA gyrase inhibition with IC50values between 15.9 and 169 muM. Molecular docking experiments were conducted to study the binding modes of inhibitors.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 106092-11-9 is helpful to your research., Synthetic Route of 106092-11-9
Reference：
Thiazole | C3H31NS – PubChem,
Thiazole | chemical compound | Britannica