Some scientific research about 5-Bromo-2-nitrothiazole

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 182692-69-9, help many people in the next few years., Reference of 182692-69-9

Reference of 182692-69-9, An article , which mentions 182692-69-9, molecular formula is C3HBrN2O2S. The compound – 5-Bromo-2-nitrothiazole played an important role in people’s production and life.

High-throughput screening with cyclin-dependent kinase 5 (cdk5)/p25 led to the discovery of N-(5-isopropyl-thiazol-2-yl)isobutyramide (1). This compound is an equipotent inhibitor of cdk5 and cyclin-dependent kinase 2 (cdk2)/cyclin E (IC50 = ca. 320 nM). Parallel and directed synthesis techniques were utilized to explore the SAR of this series. Up to 60-fold improvements in potency at cdk5 and 12-fold selectivity over cdk2 were achieved.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 182692-69-9, help many people in the next few years., Reference of 182692-69-9

Reference：
Thiazole | C3H6067NS – PubChem,
Thiazole | chemical compound | Britannica