Reference of 161797-99-5, An article , which mentions 161797-99-5, molecular formula is C13H13NO3S. The compound – Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate played an important role in people’s production and life.
During the present study, a number of substituted thiazole derivatives have been synthesized by the reaction of 4-hydroxybezene-1-carbothiomide and ethyl-2-chloro acetoacetate to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate. The latter reacts with PPA, HMTA and acetic acid to yield ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate. These compounds further react with di-bromo alkane and 4-hydroxy coumarin to give the final thiazole derivatives. These are characterized by elemental analysis, IR and 1H NMR spectra, and have been screened for their antimicrobial activity and found to have significant effect against the tested microorganisms. Some of the synthesized thiazole derivatives are found to exhibit promising activity.
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Reference：
Thiazole | C3H7802NS – PubChem,
Thiazole | chemical compound | Britannica