In an article, published in an article, once mentioned the application of 850429-61-7, Name is Methyl2-chloro-4-thiazolecarboxylate,molecular formula is C5H4ClNO2S, is a conventional compound. this article was the specific content is as follows.Safety of Methyl2-chloro-4-thiazolecarboxylate
4-Alkyl-substituted phenols and aromatic ethers were comparatively fluorinated with electrophilic fluorinating reagents such as cesium fluoroxysulfate (CFS), Selectfluor F-TEDA-BF4, and Accufluor NFTh in MeCN or MeOH. Reactions resulted in the formation of three types of products: 2-fluoro-4-alkyl-substituted corresponding compounds (5) as a result of ortho fluorination process, 4-alkyl-4-fluoro-cyclohexa-2,5- dienone compounds (6), resulting after an addition-elimination process, and 4-fluorosubstituted corresponding compounds (7) derived from ipso attack and release of the 4-alkyl group. The distribution of products depends on the bulkiness of alkyl groups at both positions and reaction media. The reaction in methanol proved more selective toward the formation of 2-fluoro derivatives. Tyramin and l-tyrozine were transformed with NFTh reagent in methanol to their fluorophenyl-substituted derivatives in good yield.
Do you like my blog? If you like, you can also browse other articles about this kind. Safety of Methyl2-chloro-4-thiazolecarboxylate. Thanks for taking the time to read the blog about 850429-61-7
Reference：
Thiazole | C3H8652NS – PubChem,
Thiazole | chemical compound | Britannica