Application of 1603-91-4, An article , which mentions 1603-91-4, molecular formula is C4H6N2S. The compound – 4-Methylthiazol-2-amine played an important role in people’s production and life.
The salts formed from alpha-aminothiazoles and alpha-bromo ketones (RCOCH2Br) have been basified, and the products converted into amides. Examination of the amides established that they are 2-acylimino-2,3- dihydrothiazoles rather than 2-acylaminothiazoles. Thus the alpha-bromo ketones attack the endo-N of the 2-aminothiazoles, and the imidazo[2,1-b] thiazoles obtained by cyclising the salts have the substituent (R) of the bromo ketone at position 6. Efficient procedures have been developed for preparing a range of imidazo[2,1-b]thiazoles. Related reactions of 2-aminothiazoles, with an alpha-bromo aldehyde and with ethyl bromoacetate, have been studied.
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Reference：
Thiazole | C3H9616NS – PubChem,
Thiazole | chemical compound | Britannica