20485-41-0, Name is 4-Methylthiazole-5-carboxylic acid, molecular formula is C5H5NO2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 20485-41-0, Formula: C5H5NO2S
Methods for the conversion of aliphatic acids to alkyl halides have progressed significantly over the past century, however, the analogous decarboxylative bromination of aromatic acids has remained a longstanding challenge. The development of efficient methods for the synthesis of aryl bromides is of great importance as they are versatile reagents in synthesis and are present in many functional molecules. Herein we report a transition metal-free decarboxylative bromination of aromatic acids. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggests that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C5H5NO2S. In my other articles, you can also check out more blogs about 20485-41-0
Reference：
Thiazole | C3H5833NS – PubChem,
Thiazole | chemical compound | Britannica