A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 78364-55-3, Name is 6-Fluoro-2-hydrazinylbenzo[d]thiazole, molecular formula is C7H6FN3S. In a Article，once mentioned of 78364-55-3, Quality Control of: 6-Fluoro-2-hydrazinylbenzo[d]thiazole
A new series of benzothiazole Schiff bases 3-29 was synthesized and screened for antitumor activity against cervical cancer (Hela) and kidney fibroblast cancer (COS-7) cell lines. Results indicated that compounds 3, 14, 19, 27 and 28 have promising activity against Hela cell line with IC50 values of 2.41, 3.06, 6.46, 2.22 and 6.25 mumol/L, respectively, in comparison to doxorubicin as a reference antitumor agent (IC50 2.05 mumol/L). In addition, compound 3 displayed excellent activity against COS-7 cell line with IC50 value of 4.31 mumol/L in comparison to doxorubicin (IC50 3.04 mumol/L). In the present work, structure based pharmacophore mapping, molecular docking, protein-ligand interaction, fingerprints and binding energy calculations were employed in a virtual screening strategy to identify the interaction between the compounds and the active site of the putative target, EGFR tyrosine kinase. Molecular properties, toxicity, drug-likeness, and drug score profiles of compounds 3, 14, 19, 27, 28 and 29 were also assessed.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Quality Control of: 6-Fluoro-2-hydrazinylbenzo[d]thiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 78364-55-3, in my other articles.
Reference：
Thiazole | C3H7053NS – PubChem,
Thiazole | chemical compound | Britannica