19952-47-7, Name is 2-Amino-4-chlorobenzothiazole, molecular formula is C7H5ClN2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 19952-47-7, Quality Control of: 2-Amino-4-chlorobenzothiazole
Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the fundamental reaction of CO2 hydration in all living organisms, being actively involved in the regulation of a plethora of patho/physiological conditions. A series of benzothiazole-based sulfonamides were synthesized and tested as possible CA inhibitors. Their inhibitory activity was assessed against the cytosolic human isoforms hCA I and hCA II and the transmembrane hCA IX and hCA XII. Several of the investigated derivatives showed interesting inhibition activity and selectivities for inhibiting hCA IX and hCA XII over the off-target ones hCA I and hCA II. Furthermore, computational procedures were used to investigate the binding mode of this class of compounds, within the active site of hCA IX.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: 2-Amino-4-chlorobenzothiazole. In my other articles, you can also check out more blogs about 19952-47-7
Reference：
Thiazole | C3H10042NS – PubChem,
Thiazole | chemical compound | Britannica