Can You Really Do Chemisty Experiments About 4-(Trifluoromethyl)thiazol-2-amine

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 349-49-5. In my other articles, you can also check out more blogs about 349-49-5

349-49-5, Name is 4-(Trifluoromethyl)thiazol-2-amine, molecular formula is C4H3F3N2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 349-49-5, SDS of cas: 349-49-5

We report herein a synthetic protocol for the preparation of 1,3-dibromo-1,1-difluoro-2-propanone, a new synthon used for the first time in a reaction with aromatic amines and sodium thiocyanate, leading to thiazoles which are useful candidates in drug discovery programs. The new synthon allows to introduce a bromodifluoromethyl group at the C4 of the thiazole, and it is amenable of further transformation such as the Br/F exchange useful in radiopharmaceutics. Application of the strategy to the preparation of a precursor of the biologically relevant DF2755Y is also reported.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 349-49-5. In my other articles, you can also check out more blogs about 349-49-5

Reference：
Thiazole | C3H4892NS – PubChem,
Thiazole | chemical compound | Britannica