A new application about Benzo[d]thiazole-2-carbonitrile

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In an article, published in an article, once mentioned the application of 2602-85-9, Name is Benzo[d]thiazole-2-carbonitrile,molecular formula is C8H4N2S, is a conventional compound. this article was the specific content is as follows.Safety of Benzo[d]thiazole-2-carbonitrile

Liver tissue engineering is going to be an effective treatment for end-stage liver disease. In this work, we distributed bone marrow mesenchymal stem cells (BMSCs) into a fast-forming hydrogel system to develop a liver-mimicking construct for liver regeneration. The advantage of this hydrogel system was that this BMSC-encapsulating hydrogel could be formed via a bioorthogonal reaction between 2-cyanobenzothiazole and cysteine within several seconds. Thereafter, we explored the morphology, biocompatibility, and expressions of hepatic differentiation markers of this hydrogel system. These results illustrated that this system could provide a suitable niche for BMSC proliferation and differentiation, which could aid in future biomedical research of liver regeneration.

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Reference:
Thiazole | C3H7541NS – PubChem,
Thiazole | chemical compound | Britannica