Some scientific research about 4-(2-Amino-4-thiazolyl)phenol

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 57634-55-6 is helpful to your research., Application of 57634-55-6

Application of 57634-55-6, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 57634-55-6, Name is 4-(2-Amino-4-thiazolyl)phenol, molecular formula is C9H8N2OS. In a Article,once mentioned of 57634-55-6

The identification of a proper lead compound for fructose 1,6-bisphosphatase (FBPase) is a critical step in the process of developing novel therapeutics against type-2 diabetes. Herein, we have successfully generated a library of allosteric inhibitors against FBPase as potential anti-diabetic drugs, of which, the lead compound 1b was identified through utilizing a virtual high-throughput screening (vHTS) system, which we have developed. The thiazole-based core structure was synthesized via the condensation of alpha-bromo-ketones with thioureas and substituents on the two aryl rings were varied. 4c was found to inhibit pig kidney FBPase approximately fivefold better than 1b. In addition, we have also identified 10b, a tight binding fragment, which can be use for fragment-based drug design purposes.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 57634-55-6 is helpful to your research., Application of 57634-55-6

Reference:
Thiazole | C3H4584NS – PubChem,
Thiazole | chemical compound | Britannica