A new application about 4-Methylthiazole-5-carbaldehyde

Do you like my blog? If you like, you can also browse other articles about this kind. name: 4-Methylthiazole-5-carbaldehyde. Thanks for taking the time to read the blog about 82294-70-0

In an article, published in an article, once mentioned the application of 82294-70-0, Name is 4-Methylthiazole-5-carbaldehyde,molecular formula is C5H5NOS, is a conventional compound. this article was the specific content is as follows.name: 4-Methylthiazole-5-carbaldehyde

A convenient and efficient synthesis of multi-substituted thiazole-containing tetrahydropyridine moieties was reported using the phosphine-catalyzed Aza-Rauhut-Currier reaction with excellent yields and diastereoselectivity. Thiazole-containing tetrahydropyridines were further transformed into the corresponding piperidine derivatives. The biological activity of the title compounds was explored; they exhibited moderate insecticidal activity against Aphis laburni Kaltenbach at 100 mug mL. A 3D QSAR model accurately predicted the insecticidal activity of the structurally diverse set of test compounds. Thiazole-containing tetrahydropyridines were active against normal fungi and also had good activity against resistant fungi mutations without cross resistance; thus, these compounds will be valuable for resistance management. The predicted potential fungicidal target of the title compounds is fumarate reductase.

Do you like my blog? If you like, you can also browse other articles about this kind. name: 4-Methylthiazole-5-carbaldehyde. Thanks for taking the time to read the blog about 82294-70-0

Reference:
Thiazole | C3H5787NS – PubChem,
Thiazole | chemical compound | Britannica