Final Thoughts on Chemistry for 4-Methyl-5-thiazoleethanol

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4-Methyl-5-hydroxyethylthiazole kinase (ThiM) participates in thiamin biosynthesis as the key enzyme in its salvage pathway. We purified and characterized ThiM from Escherichia coli. It has broad substrate specificity toward various nucleotides and shows a preference for dATP as a phosphate donor over ATP. It is activated by divalent cations, and responds more strongly to Co 2+ than to Mg2+.

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Reference:
Thiazole | C3H5578NS – PubChem,
Thiazole | chemical compound | Britannica