Top Picks: new discover of 5-Nitrothiazol-2-amine

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 121-66-4 is helpful to your research., Recommanded Product: 121-66-4

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.121-66-4, Name is 5-Nitrothiazol-2-amine, molecular formula is C3H3N3O2S. In a Article,once mentioned of 121-66-4, Recommanded Product: 121-66-4

A novel series of 5-nitroimidazole-piperazines (4a?j) and 5-nitrothiazole-piperazine (7a?j) have been prepared in good yields. The antigiardial and antitrichomonal activities of these new compounds were evaluated. Majority of the compounds was found to be more active against Giardia lamblia as compared to metronidazole at 24 hours of incubation. After 48 hours of incubation, compounds 4b, 4f, 7c and 7j showed better activity against G. lamblia with IC50 of 15.3, 11.4, 5.9, 13.5 muM respectively compared to metronidazole (17.4 muM). Compounds 4a?j and 7a?j exhibited anti-parasitic activity against T. vaginalis with IC50 ranging from 16.4?88.7 muM and 1.2?86.7 muM at 24 hours and 48 hours of incubation respectively. Compounds 4c and 7e were 15 times more potent than the standard drug, metronidazole.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 121-66-4 is helpful to your research., Recommanded Product: 121-66-4

Reference:
Thiazole | C3H9537NS – PubChem,
Thiazole | chemical compound | Britannica