Discovery of 850429-61-7

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Synthetic Route of 850429-61-7, An article , which mentions 850429-61-7, molecular formula is C5H4ClNO2S. The compound – Methyl2-chloro-4-thiazolecarboxylate played an important role in people’s production and life.

Lewis acid promoted substitution reactions employing Meldrum’s acid and 5-methyl Meldrum’s acid as carbon-based leaving groups are described which transform unstrained quaternary and tertiary benzylic Csp 3-Csp3 bonds into Csp3-X bonds (X = C, H, N). Importantly, this reaction has a broad scope in terms of both suitable substrates and nucleophiles with good to excellent yields obtained (typically >90%).

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Reference:
Thiazole | C3H8593NS – PubChem,
Thiazole | chemical compound | Britannica