Discovery of 5-Methylthiazole-2-carboxylic acid

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Electric Literature of 61291-21-2. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 61291-21-2, Name is 5-Methylthiazole-2-carboxylic acid

New compounds containing [1,2,4]triazolo [1,5-a]pyridine (I), pyrazolo [1,5-a]pyridine (II), 1H-1,3-benzodiazole (III) and imidazo [1,2-a]pyrimidine (IV) backbones were designed and synthesized for PDE10A interaction. Among these compounds, 1H-1,3-benzodiazoles and imidazo [1,2-a]pyrimidines showed the highest affinity for PDE10A enzyme as well as good metabolic stability. Both classes of compounds were identified as selective and potent PDE10A enzyme inhibitors.

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Reference:
Thiazole | C3H6518NS – PubChem,
Thiazole | chemical compound | Britannica