9-Sep-2021 News Final Thoughts on Chemistry for 2-Amino-4-chlorobenzothiazole

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A regioselective [2+3] cyclocondensation between chlorocarbonylsulfenyl chloride (3) and 2-aminobenzothiazoles gave 3H-1,2,4-thiadiazolo[3,4-b]benzothiazol-3-ones (1). Some heterocycles (1) and their isosteric known 5-substituted 2-methyl-imidazo[2,1-b]benzothiazoles (2) which were prepared from 2-aminobenzothiazoles via two steps, showed significant fungicidal activities.

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Reference:
Thiazole | C3H10070NS – PubChem,
Thiazole | chemical compound | Britannica