22-Sep-21 News Archives for Chemistry Experiments of 5-Bromobenzothiazole

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Synthetic Route of 768-11-6. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 768-11-6, Name is 5-Bromobenzothiazole

A mild, copper-catalyzed coupling of organoindium reagents with nitrogen-containing aromatic heterocycles and chloroformates is described. This reaction proceeds with a range of organoindium reagents, yielding predominately or exclusively the 1,4-addition products with pyridine. In addition, a range of other nitrogen-containing heterocycles can be employed in this reaction (e.g. benzoxazole, benzothiazole, phthalazine). As an illustration of the utility of this reaction, this heterocycle functionalization is coupled with a subsequent oxidation to achieve the one-pot synthesis of functionalized pyridine and benzothiazole derivatives.

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Reference:
Thiazole | C3H6154NS – PubChem,
Thiazole | chemical compound | Britannica