3034-53-5, 2-Bromothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a cooled solution (-78°C) of n-butyllithium (1.7M in pentane, 323mL,550.8 mmol, 1.5 eq) in tetrahydrofuran (150 mL) under nitrogen was added 2- bromothiazole (60 g, 367.2mmol). The resulting suspension was stirred below – 78°C for 45 min. The lithiated thiazole solution was transferred via cannula to a solution of dimethylformamide (25 mL) in tetrahydrofuran (200 mL) at -78°C. The reaction was allowed to warm to room temperature over 3 h and quenched by the addition of water (100 mL). The aqueous phase was extracted with ethyl acetate (3*100 mL). Combined organic extracts were dried over anhydrous magnesium sulfate, filtered and reduced to afford 2-formylthiazole as a crude oil.
3034-53-5, 3034-53-5 2-Bromothiazole 76430, athiazole compound, is more and more widely used in various fields.
Reference:
Patent; BIOENERGENIX; MCCALL, John; KELLY, Robert, C.; ROMERO, Donna, L.; WO2014/66795; (2014); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica