Some tips on 943-03-3

The synthetic route of 943-03-3 has been constantly updated, and we look forward to future research findings.

943-03-3,943-03-3, 6-Methoxybenzo[d]thiazole-2-carbonitrile is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The methoxycarbonitrile derivative (1 eq) was mixed with pyridinium chloride (5 eq) under argon and heated to 210°C for 30 minutes. The resulting mixture was partitioned between distilled water and dicloromethane, and the organic layers were concentrated under vacuum. The crude product was dissolved in 5 percent Na2CO3 (50 ml) and filtered before addition of HCl until pH ?4.0. The aqueous layer was extracted with dichloromethane (50 mL) and the organic layers removed under vacuum yielding pure product (>98percent).

The synthetic route of 943-03-3 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Rothweiler, Ulli; Eriksson, Jonas; Stensen, Wenche; Leeson, Frederick; Engh, Richard A.; Svendsen, John S.; European Journal of Medicinal Chemistry; vol. 94; (2015); p. 140 – 148;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica