556-90-1,556-90-1, 2-aminothiazol-4(5H)-one is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To the magnetically stirred solution of 17 (232 mg, 2 mmol) in HOAc (7 mL), was added NaOAc (500 mg, 6 mmol). After 15 min 3,4-dimethoxybenzaldhyde (16a, 400 mg, 2.4 mmol) was added and the reaction mixture was heated under reflux for 72 h. The HOAc was removed under reduced pressure and the resultant solid was washed successively with water, methanol and EtOAc to obtain the desired products as solid. 10.2.1.8 5-(4-Chloro-3-nitrobenzylidene)-2-iminothiazolidin-4-one (14h) Orange solid; mp > 200 C; 338 mg, 60% yield; IR (neat) numax = 3214, 3009, 1965, 1693, 1667 cm-1; 1H NMR (400 MHz, CD3SOCD3) delta 9.58 (s, 1H), 9.33 (s, 1H) 8.20 (s, 1H), 7.82-7.89 (m, 2H), 7.62 (s, 1H); 13C NMR (100 MHz, CD3SOCD3): delta 180.28, 175.47, 148.21, 135.23, 134.26, 133.46 132.95, 126.39, 125.98, 125.79; HRMS (ESI-TOF): m/z calculated for C10H6ClN3O3S [M+Na]+, 305.9716; found 305.9712.
The synthetic route of 556-90-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Arfeen, Minhajul; Bhagat, Shweta; Patel, Rahul; Prasad, Shivcharan; Roy, Ipsita; Chakraborti, Asit K.; Bharatam, Prasad V.; European Journal of Medicinal Chemistry; vol. 121; (2016); p. 727 – 736;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica