1011-40-1, 2-Phenylthiazole-5-carbaldehyde is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2-phenyl-thiazole-5-carbaldehyde 41 (Silberg A. et al. Chem. Ber. 1964, 97, 1684-1687) (3.1 g, 16.4 mmol) was treated with malonic acid (2.4 g, 23.0 mmol), pyridine (3 mL) and piperidine (0.16 mL) and the mixture was heated at reflux for 6 hours before being cooled to room temperature. The mixture was then poured into water (50 mL) with stirring. The resulted yellow solid 42 was filtered, washed with water and air-dried (2.45 g). 1H NMR (400 MHz, d6-DMSO) delta: 6.25 (d, J=15.7 Hz, 1H), 7.53 (m, 3H), 7.78 (d, J=15.7 Hz, 1H), 7.97 (m, 2H), 8.23 (s, 1H).
1011-40-1, 1011-40-1 2-Phenylthiazole-5-carbaldehyde 2763706, athiazole compound, is more and more widely used in various fields.
Reference：
Patent; Tularik Inc.; US2004/97485; (2004); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica