With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6294-52-6,5,6-Dimethoxybenzo[d]thiazol-2-amine,as a common compound, the synthetic route is as follows.
General procedure: Corresponding benzo[d]thiazol-2-amine (3 and 4) (0.025 mol) and triethylamine (0.030 mol,4.24 mL) were dissolved in THF (50 mL). This mixture was kept on an ice bath andchloroacetyl chloride (0.030 mol, 2.37 mL) in THF (10 ml) was added dropwise with constantstirring. After this stage, the content was allowed to stir for an additional 1 h at roomtemperature. THF was evaporated, the raw product was washed with water, dried andrecrystallized from ethanol.2,3, 6294-52-6
6294-52-6 5,6-Dimethoxybenzo[d]thiazol-2-amine 94938, athiazole compound, is more and more widely used in various fields.
Reference：
Article; Demir Oezkay, Uemide; Can, Oezguer Devrim; Sa?l?k, Beguem Nurpelin; Acar Cevik, Ulviye; Levent, Serkan; Oezkay, Yusuf; Ilg?n, Sinem; Atl?, Oezlem; Bioorganic and Medicinal Chemistry Letters; vol. 26; 22; (2016); p. 5387 – 5394;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica