Downstream synthetic route of 3622-35-3

The synthetic route of 3622-35-3 has been constantly updated, and we look forward to future research findings.

3622-35-3, Benzo[d]thiazole-6-carboxylic acid is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

3622-35-3, Step A. Benzothiazole-6-carbonyl chloride Under anhydrous conditions, a mixture of benzothiazole-6-carboxylic acid (1.0 g, 5.6 mmol) and oxalyl chloride (0.5 mL, 5.6 mmol) in dichloromethane (25 mL) containing a catalytic amount of N,N-dimethylformamide was stirred at ambient temperature for 3 hours. Removal of the solvent in vacuo provided a quantitative yield of the acid chloride as a light brown solid, which was used as such in the next step.

The synthetic route of 3622-35-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Wyeth; EP1149104; (2002); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica