With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15864-32-1,2-Amino-6-bromobenzothiazole,as a common compound, the synthetic route is as follows.
2. A suspension of 6-bromobenzothiazol-2-ylamine (2. 29 g, 10 mmol) prepared above in sodium hydroxide (40 mL of a 6 M solution, 240 mmol) was refluxed under argon overnight. The reaction mixture was cooled in an ice bath and was acidified to between pH 3 and 5 with conc. HCI. The resulting precipitate was isolated by filtration, washed with water and dried under high vacuum to afford the crude product that was used in the following reaction without further purification., 15864-32-1
As the paragraph descriping shows that 15864-32-1 is playing an increasingly important role.
Reference：
Patent; KINETEK PHARMACEUTICALS, INC.; WO2004/11460; (2004); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica