With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15864-32-1,2-Amino-6-bromobenzothiazole,as a common compound, the synthetic route is as follows.
General procedure: To a mixture of 6-bromobenzo[d]thiazol-2-amine (470 mg, 2.01 mmol) and CuBr2 (760 mg, 3.42 mmol) in MeCN (10 mL) at 0 C, was added iso-pentyl nitrite (280 mg, 2.41 mmol) dropwise. The reaction mixture was stirred at 0 C for 1 h and then H2O (100 mL) was added. The resulting precipitate was filtered and dried in vacuum to give the title compound (515 mg, 87%) as a brown solid., 15864-32-1
As the paragraph descriping shows that 15864-32-1 is playing an increasingly important role.
Reference:
Article; Yang, Zhaohui; Ma, Haikuo; Sun, Zhijian; Luo, Lusong; Tian, Sheng; Zheng, Jiyue; Zhang, Xiaohu; Bioorganic and Medicinal Chemistry Letters; vol. 25; 17; (2015); p. 3665 – 3670;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica