With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.939-69-5,6-Hydroxybenzo[d]thiazole-2-carbonitrile,as a common compound, the synthetic route is as follows.,939-69-5
General procedure: The hydroxy- or methoxycarbonitrile derivative (1 eq) was added to the cysteine derivative (1.05 eq) and sodium carbonate (3 eq) in 5 ml water. The mixture was stirred at room temperature for three hours before addition of dilute HCl (1 M) to pH ? 3.5 ? 4.0. The product was isolated by extraction with diethyl ether, washed by water, followed by evaporation
939-69-5 6-Hydroxybenzo[d]thiazole-2-carbonitrile 9881912, athiazole compound, is more and more widely used in various fields.
Reference：
Article; Rothweiler, Ulli; Eriksson, Jonas; Stensen, Wenche; Leeson, Frederick; Engh, Richard A.; Svendsen, John S.; European Journal of Medicinal Chemistry; vol. 94; (2015); p. 140 – 148;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica