3034-53-5, 2-Bromothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1) A mixture of 2-bromothiazole (0.9 ml, 10 mmols), 4-formylphenylboronic acid (1.65 g, 11 mmols), sodium carbonate (2.65 g, 25 mmols), toluene (150 ml), ethanol (30 ml) and water (30 ml) was stirred in an argon atmosphere at room temperature for 30 minutes. Tetrakis(triphenylphosphine)palladium(0) (0.58 mg, 0.5 mmols) was added thereto and heated under reflux for 15 hours. The reaction mixture was cooled, poured into water, and extracted with ethyl acetate. The extract was washed with water and brine, then dried with anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was purified through silica gel column chromatography, and then recrystallized from ethyl acetate/hexane to give 4-(2-thiazolyl)benzaldehyde (1.4 g, 74 %).m.p. 91.5-92.5C Elemental Analysis for C10H7NOS: Calcd.: C, 63.47; H, 3.73; N, 7.40 Found: C, 63.67; H, 3.60; N, 7.316 1H-NMR (CDCl3) delta: 7.46(1H,d,J=3.2Hz), 7.95-7.99(3H,m),
3034-53-5, As the paragraph descriping shows that 3034-53-5 is playing an increasingly important role.
Reference:
Patent; Takeda Chemical Industries, Ltd.; EP1123918; (2001); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica