64987-16-2,64987-16-2, Methyl 2-(2-aminothiazol-4-yl)acetate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
thyl 2-(2-bromothiazol-4-yl)acetate Methyl 2-(2-aminothiazol-4-yl)acetate (5g, 26.8mmol) was added under nitrogen to a solution of copper(ll) bromide (6.77g, 30mmol) and f-butyl nitrite (4.79ml, 40mmol) in acetonitrile (20ml) at -20C. The reaction mixture was slowly warmed to room temperature and stirred for two hours. The solution was then diluted with diethyl ether and washed with 25ml of 10 percent hydrochloric acid solution; the aqueous phase was extracted with 20ml of diethyl ether. The combined organic phases were dried and evaporated to dryness. The residue was purified by a standard method to yield the title compound. LC-MS : m/z (M+H) = = 235.9
The synthetic route of 64987-16-2 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; AGIOS PHARMACEUTICALS, INC.; LEMIEUX, Rene M.; POPOVICI-MULLER, Janeta; SALITURO, Francesco G.; SAUNDERS, Jeffrey O.; TRAVINS, Jeremey; CHEN, Yongsheng; WO2014/79150; (2014); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica