131106-70-2, 6-(Trifluoromethyl)benzo[d]thiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
0.05 mole of 6-trifluoromethylbenzothiazole was added to 20 ml of ethyl ether at a temperature ranging -65 to -55 C. On the other hand, 0.05 mole of n-butyl lithium was added to 155 ml of ethyl ether. The former mixture was added to the latter one in a dropwise fashion for 15 minutes. In addition, 0.05 mole of triphenyl bromosilane was added to 20 ml of ethyl ether. This solution was added to the above mixed solution in a dropwise fashion at -45 C. for 5 minutes. It was heated up to -13 C. for 4 hours and maintained at a temperature of -13 to -10 C. for 4 hours. Then, an aqueous ammonium chloride solution and ice were added to the resulting solution to separate an ethyl ether layer. The separated ethyl ether layer was washed with water, dried with sodium sulfate, and treated under reduced pressure to remove a solution. Then, a semi-solid phase material was extracted with 300 ml of boiling petroleum and treated under reduced pressure to remove the solution. When the solution was removed, the extract was washed with 50 ml of ethanol and 15 ml of benzene and then, recrystaled with a mixture of 6 ml of benzene and 15 ml of ethanol to thereby produce a yellow solid at a yield of 23%.
131106-70-2, The synthetic route of 131106-70-2 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; SAMSUNG ELECTRONICS CO., LTD.,; Industry-University Cooperation Foundation, Hanyang University; US2008/207905; (2008); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica