494769-34-5, N-Boc-2-Amino-4-formylthiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 1 Synthesis of N-tert-butyl-alpha-[2-N-(1,1-dimethylethoxycarbonyl) aminothiazol-4-yl]nitrone (28) 2.0 g (8.76 mmol) of compound 22, 5.42g (52.57 mmol) of 2-methyl-2-nitropropane (27), and 2.86 g (43.81 mmol) of zinc were placed in a round-bottomed flask along with 95% ethanol (50 mL) and cooled to 0 C. 4.21 g (70.11 mmol) of acetic acid was added slowly with stirring. The solution was allowed to come to room temperature, stirred for 6 hours. CH2Cl2 was added to the reaction mixture and it was filtered through a Celite pad and concentrated under reduced pressure. The residue was purified by short flash column chromatography (silica, Hex_EtOAc=1:1) to give 1.28 g (4.28 mmol) of compound 28 as a yellow solid in 49% yield. 1H NMR (CDCl3): 9.9 (br s, 1H), 8.82 (s, 1H), 7.87 (s, 1H), 1.60 (s, 9H), 1.54 (s, 6H); 13C NMR (CDCl3): 159.54, 152.35, 141.53, 125.78,
494769-34-5, 494769-34-5 N-Boc-2-Amino-4-formylthiazole 23138686, athiazole compound, is more and more widely used in various fields.
Reference：
Patent; Ko, Sung-Bo; Oh, Eu-Gene; Kim, Eon-Kyeom; Kim, Won-Yeob; Choi, Dennis W.; Dugan, Laura L.; Koh, Jae-Young; Won, Moo-Ho; Wie, Myung-Bok; US2003/220337; (2003); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica