Recommanded Product: 1416134-49-0. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (2S,5R)-5-((Benzyloxy)amino)piperidine-2-carboxamide, is researched, Molecular C13H19N3O2, CAS is 1416134-49-0, about A New Synthetic Route to Avibactam: Lipase Catalytic Resolution and the Simultaneous Debenzylation/Sulfation. Author is Wang, Tao; Du, Liang-Dong; Wan, Ding-jian; Li, Xiang; Chen, Xin-Zhi; Wu, Guo-Feng.
An efficient synthesis of avibactam starting from com. available ethyl-5-hydroxypicolinate was completed in ten steps and 23.9% overall yield. The synthesis features a novel lipase-catalyzed resolution, in the preparation of (2S,5S)-5-hydroxypiperidine-2-carboxylate acid, which are valuable precursors of the key intermediate Et (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxylate. An optimized one-pot debenzylation / sulfation reaction, followed by cation exchange, gave the avibactam sodium salt on a 400.0 g scale.
There is still a lot of research devoted to this compound(SMILES：O=C([C@H]1NC[C@H](NOCC2=CC=CC=C2)CC1)N)Recommanded Product: 1416134-49-0, and with the development of science, more effects of this compound(1416134-49-0) can be discovered.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica