Chen, Yanhong; Xiang, Haoyue; Tan, Cun; Xie, Yuyuan; Yang, Chunhao published the article 《A tandem copper (II)-promoted synthesis of 2-substituted pyrrolo[2,1-f][1,2,4] triazin-4(3H)-ones》. Keywords: aldehyde aminopyrroleamide annulation cupric chloride catalyst; acetal aminopyrroleamide annulation cupric chloride catalyst; pyrrolotriazinone preparation.They researched the compound: 1-Aminopyrrole-2-carboxamide( cas:159326-69-9 ).Application of 159326-69-9. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:159326-69-9) here.
Annulation of 1-amino-1H-pyrrole-2-amides with various substituted benzaldehydes, heteroaryl aldehydes, alkyl aldehydes or even acetals, promoted by cupric chloride, to synthesize 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones was carried out. This approach provides a useful method for constructing the privileged structure in medicinal chem. Electron-donating groups on both partners could accelerate the reaction.
There is still a lot of research devoted to this compound(SMILES：O=C(C1=CC=CN1N)N)Application of 159326-69-9, and with the development of science, more effects of this compound(159326-69-9) can be discovered.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica