With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.10200-59-6,2-Thiazolecarboxaldehyde,as a common compound, the synthetic route is as follows.
Hydroxylamine hydrochloride (9.03 g, 130 mmol) was added to a solution of 1 ,3-thiazole-2-carbaldehyde (14.71 g, 130 mmol) and pyridine (10.5 mL, 130 mmol) in DCM (100 mL). The reaction mixture was stirred overnight at room temperature and then washed twice with water. The organic layer was dried over MgS04 and then evaporated under reduced pressure to give 15.26 g of 1 ,3-thiazole-2-carbaldehyde oxime (yield 92percent)., 10200-59-6
As the paragraph descriping shows that 10200-59-6 is playing an increasingly important role.
Reference£º
Patent; UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE – CNRS -; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE); INSTITUT PASTEUR DE LILLE; DEPREZ, Benoit; WILLAND, Nicolas; FLIPO, Marion; DESROSES, Matthieu; BAULARD, Alain; LEROUX, Florence; WO2013/60744; (2013); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica