5398-36-7, Ethyl 2-aminothiazole-4-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of compound 1 (7.8 g, 45.3mmol), Boc2O (9.9 g, 45.3 mmol), DMAP (0.1 g, 0.82mmol) in CH2Cl2 (50 mL) was stirred at room temperature for 4 h. After completion of the reaction, the mixture was washed with H2O (30mL), brine (30 mL), the organic layer was dried over anhydrous Na2SO4, filtered and concentrated in vacuo. The crude product was purified by column chromatograph on silica gel (200-300 mesh) by ethyl acetate and petroleum ether (v/v = 1:2) as eluent to afford 2 as a light yellow solid (11.5 g, yield 93.5%).
5398-36-7, The synthetic route of 5398-36-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Li, Feng-Yun; Guo, Xiao-Feng; Fan, Zhi-Jin; Zhang, Yu-Qing; Zong, Guang-Ning; Qian, Xiao-Lin; Ma, Liu-Yong; Chen, Lai; Zhu, Yu-Jie; Tatiana, Kalinina; Morzherin, Yury Yu.; Belskaya, Nataliya P.; Chinese Chemical Letters; vol. 26; 10; (2015); p. 1315 – 1318;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica