The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-Aminopyrrole-2-carboxamide, is researched, Molecular C5H7N3O, CAS is 159326-69-9, about A tandem copper (II)-promoted synthesis of 2-substituted pyrrolo[2,1-f][1,2,4] triazin-4(3H)-ones, the main research direction is aldehyde aminopyrroleamide annulation cupric chloride catalyst; acetal aminopyrroleamide annulation cupric chloride catalyst; pyrrolotriazinone preparation.Category: thiazole.
Annulation of 1-amino-1H-pyrrole-2-amides with various substituted benzaldehydes, heteroaryl aldehydes, alkyl aldehydes or even acetals, promoted by cupric chloride, to synthesize 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones was carried out. This approach provides a useful method for constructing the privileged structure in medicinal chem. Electron-donating groups on both partners could accelerate the reaction.
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Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica