Extracurricular laboratory: Synthetic route of 92-71-7

Although many compounds look similar to this compound(92-71-7)Recommanded Product: 2,5-Diphenyloxazole, numerous studies have shown that this compound(SMILES:C1(C2=CC=CC=C2)=NC=C(C3=CC=CC=C3)O1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Hydrogen Isotope Exchange Catalyzed by Ru Nanocatalysts: Labelling of Complex Molecules Containing N-Heterocycles and Reaction Mechanism Insights, published in 2020-04-21, which mentions a compound: 92-71-7, Name is 2,5-Diphenyloxazole, Molecular C15H11NO, Recommanded Product: 2,5-Diphenyloxazole.

Ruthenium nanocatalysis can provide effective deuteration and tritiation of oxazole, imidazole, triazole and carbazole substructures in complex mols. using D2 or T2 gas as isotopic sources. Depending on the substructure considered, this approach does not only represent a significant step forward in practice, with notably higher isotope uptakes, a broader substrate scope and a higher solvent applicability compared to existing procedures, but also the unique way to label important heterocycles using hydrogen isotope exchange. In terms of applications, the high incorporation of deuterium atoms, allows the synthesis of internal standards for LC-MS quantification. Moreover, the efficacy of the catalyst permits, even under subatmospheric pressure of T2 gas, the preparation of complex radiolabeled drugs owning high molar activities. From a fundamental point of view, a detailed DFT-based mechanistic study identifying undisclosed key intermediates, allowed a deeper understanding of C-H (and N-H) activation processes occurring at the surface of metallic nanoclusters.

Although many compounds look similar to this compound(92-71-7)Recommanded Product: 2,5-Diphenyloxazole, numerous studies have shown that this compound(SMILES:C1(C2=CC=CC=C2)=NC=C(C3=CC=CC=C3)O1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica