Zheng, Jun;Woerl, Benjamin;Breit, Bernhard published 《Rhodium-Catalyzed Chemo-, Regio-, and Enantioselective Allylation of 2-Aminothiazoles with Terminal Allenes》 in 2019. The article was appeared in 《European Journal of Organic Chemistry》. They have made some progress in their research.Electric Literature of C7H5N3O2S The article mentions the following:
A rhodium-catalyzed chemo-, regio- and enantioselective intermol. coupling reaction of 2-aminobenzothiazoles with terminal allenes is reported. The new reaction displays a wide substrate scope for both reaction partners to deliver the allylation products in good yields, with excellent regio- and enantioselectivity. This novel methodol. was further applied in an efficient synthesis of chiral isothiourea. And 6-Nitrobenzo[d]thiazol-2-amine (cas: 6285-57-0) was used in the research process.
6-Nitrobenzo[d]thiazol-2-amine(cas:6285-57-0) has been used:
as model analyte for voltammetric determination of electrochemically reducible organic substances;in the synthesis of 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide derivatives;in the preparation of push-pull nonlinear optical chromophores containing thiazole and benzothiazole acceptors;as a base in dye production by diazotation reaction.
in the synthesis of 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide derivatives;
in the preparation of push-pull nonlinear optical chromophores containing thiazole and benzothiazole acceptors;
as a base in dye production by diazotation reaction.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica