Quality Control of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate《Review on nitazoxanide: a broad spectrum antiparasitic agent》 was published in 2021. The authors were Kothari, Ruchita M.;Patil, Javesh K.;Jain, Akash S.;Chaudhari, Hitendra S.;Dhankani, Amitkumar R.;Rokade, Yogesh B., and the article was included in《European Journal of Biomedical and Pharmaceutical Sciences》. The author mentioned the following in the article:
A review. Nitazoxanide is a thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of parasites as well as some bacteria. It has been used as a single agent to treat mixed infections with intestinal parasites i.e. protozoas and helminths. It was originally discovered in 1975 by Jean Francois Rossignol & It was initially developed as a veterinary antihelminthic with activity against intestinal nematodes, cestodes, and liver trematodes & In humans, nitazoxanide has been reported to be effective against a broad range of parasites, including Giardia lamblia, Entamoeba histolytica, Cryptosporidium parvum, Cyclospora cayetanens, etc. The main objective of this review is to study detailed profile of nitazoxanide like physicochem. properties, pharmacokinetics, clin. uses, and adverse effects of Nitazoxanide. The experimental procedure involved many compounds, such as 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate (cas: 55981-09-4) .
2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate(cas: 55981-09-4) has been approved as an orphan drug for the treatment of diarrhea in children (age, 1–11 years) and is associated with giardiasis, but it also is approved for diarrhea caused by crytosporidiosis in patients with AIDS.Quality Control of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica