3704-41-4, 2-(4-Nitrophenyl)thiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 2-(4-nitrophenyl)thiazole (6 g, 29.10 mmol, 1 eq.) in DMF (50 mL), was added NBS (15.54 g, 87.29 mmol, 3 eq.). The mixture was stirred at 80C for 15 mins and LCMS showed the reaction was complete. The mixture was poured into water (1L) and filtered. The filter cake was washed with MeOH (50 mL) and dried to give 5-bromo-2- (4- nitrophenyl)thiazole (7.3 g, crude) as a yellow solid. 1H NMR (400MHz, METHANOL-d4) delta = 8.35 (br s, 2H), 8.18 (br s, 2H), 8.07 – 7.88 (m, 1H).
3704-41-4, 3704-41-4 2-(4-Nitrophenyl)thiazole 13546655, athiazole compound, is more and more widely used in various fields.
Reference£º
Patent; CYTEIR THERAPEUTICS, INC.; CASTRO, Alfredo, C.; MCCOMAS, Casey, Cameron; VACCA, Joseph; (214 pag.)WO2019/14315; (2019); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica