Pulici, Maurizio; Quartieri, Francesca published the artcile< Traceless solid-phase synthesis of 2-amino-5-alkylidene-thiazol-4-ones>, Name: 3-Benzyl-2-thioxothiazolidin-4-one, the main research area is polymer supported rhodanine arylaldehyde Knoevenagel condensation amine resin cleavage; aminoalkyldiene thiazolone stereoselective preparation.
2-Amino-5-alkylidene-thiazol-4-ones, e.g., I, bearing two diversity points were prepared by a solid-phase strategy exploiting rhodanine as the starting material. Rhodanine was first loaded on bromo-Wang resin, subjected to Knoevenagel condensation with aldehydes, and cleaved off the resin in a traceless manner by means of an amine.
Tetrahedron Letters published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 10574-69-3 belongs to class thiazole, and the molecular formula is C10H9NOS2, Name: 3-Benzyl-2-thioxothiazolidin-4-one.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica