Potewar, Taterao M.; Ingale, Sachin A.; Srinivasan, Kumar V. published the artcile< Catalyst-free efficient synthesis of 2-aminothiazoles in water at ambient temperature>, Recommanded Product: 2-Amino-4-(3-nitrophenyl)thiazole, the main research area is bromomethyl aryl ketone substituted thiourea heterocyclization catalyst free; aryl aminothiazole fanetizole preparation.
A highly efficient and facile method has been described for the synthesis of substituted 2-aminothiazoles, e.g., I, in water without any added catalyst or co-organic solvent. The reaction was carried out at ambient temperature and the products were obtained in excellent isolated yields. The developed protocol is successfully applied for the preparation of an anti-inflammatory drug, fanetizole.
Tetrahedron published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent) (bromo). 57493-24-0 belongs to class thiazole, and the molecular formula is C9H7N3O2S, Recommanded Product: 2-Amino-4-(3-nitrophenyl)thiazole.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica