Kennington, Stuart C. D.; Taylor, Adam J.; Romea, Pedro; Urpi, Felix; Aullon, Gabriel; Font-Bardia, Merce; Ferre, Laura; Rodrigalvarez, Jesus published the artcile< Direct and Asymmetric Nickel(II)-Catalyzed Construction of Carbon-Carbon Bonds from N-Acyl Thiazinanethiones>, Electric Literature of 96-53-7, the main research area is asym nickel catalyzed carbon bond acyl thiazinanethione; peperomin D total synthesis; dimethoxyphenyl methylphenylethyl propanamide preparation crystal mol structure.
A wide array of new N-acyl thiazinanethiones are employed in a number of direct and enantioselective carbon-carbon-bond-forming reactions catalyzed by nickel(II) complexes. The electrophilic species are mostly prepared in situ from ortho esters, Me ethers, acetals, and ketals, which makes the overall process highly efficient and exptl. straightforward. Theor. calculations indicate that the reactions proceed through an open transition state in a SN1-like mechanism. The utility of this novel procedure has been demonstrated by the asym. preparation of synthetically useful intermediates and the total synthesis of peperomin D.
Organic Letters published new progress about C-C bond formation (enantioselective). 96-53-7 belongs to class thiazole, and the molecular formula is C3H5NS2, Electric Literature of 96-53-7.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica