The author of 《Synthesis and biological evaluation of some newly synthesized thiazolo-pyrimido-pyrimidobenzothiazoles》 were Pawde, A. V.; Kadam, D. B.; Vartale, S. P.. And the article was published in European Journal of Biomedical and Pharmaceutical Sciences in 2021. SDS of cas: 95-24-9 The author mentioned the following in the article:
Condensation of 2-amino-5-methylthiazole with bis(methylthio)methylene malononitrile give 6-cyano-5-imino-2-methyl-7-(methylthio)-5H-thiazolo[3,2-a]pyrimidine. Which on further condensation with various 2-amino-substituted benzothiazoles yield 12, 13-diimino-9-methyl- thiazolo[2,3-a]-4H-pyrimido[4,5-d]-4H-pyrimido[2,1-b]benzothiazoles I (R1 = H, Cl; R2 = H, Me, OMe, F, Cl, NO2; R3 = H, Me). Some of the newly synthesized compounds have been screened for their antimicrobial and antioxidant activity. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzothiazol-2-ylamine(cas: 95-24-9SDS of cas: 95-24-9)
6-Chlorobenzothiazol-2-ylamine(cas: 95-24-9) belongs to thiazoles. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities.SDS of cas: 95-24-9Their presence in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica