Analyzing the synthesis route of 14542-12-2

14542-12-2, 14542-12-2 Thiazol-2-ylmethanol 2795213, athiazole compound, is more and more widely used in various fields.

14542-12-2, Thiazol-2-ylmethanol is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Manufacturing Example 88-1-2 2-Chloromethyl-thiazole; To a mixture of thiazole-2-yl-methanol (251 mg, 2.18 mmol) described in Manufacturing Example 88-1-1 and dichloromethane (10 mL) was added thionyl chloride (191 muL, 2.62 mmol) at room temperature, which was stirred for 30 minutes. Saturated aqueous sodium hydrogencarbonate solution was added to the reaction mixture, which was then extracted with dichloromethane. The organic layer was separated, washed with water and saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated under a reduced pressure to obtain the title compound (220.5 mg, 76%).1H-NMR Spectrum (DMSO-d6) delta (ppm): 5.11 (2H, s), 7.81-7.83 (2H, m).

14542-12-2, 14542-12-2 Thiazol-2-ylmethanol 2795213, athiazole compound, is more and more widely used in various fields.

Reference£º
Patent; Tanaka, Keigo; Yamamoto, Eiichi; Watanabe, Naoaki; US2009/82403; (2009); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica