With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.344-72-9,Ethyl 2-amino-4-(trifluoromethyl)thiazole-5-carboxylate,as a common compound, the synthetic route is as follows.
Step 2: 2-(1-piperidinyl)-4-trifluoromethylthiazole-5-carboxylic Acid (A-33) Compound A-33 was prepared by the general procedure for step 2 of intermediate A-31 using compound A-32 as starting material. 1H NMR (500 MHz, CDCl3) delta 3.56 (m, 4H), 1.73 (m, 6H); LCMS (ESI) [M+1]+ 281.2., 344-72-9
As the paragraph descriping shows that 344-72-9 is playing an increasingly important role.
Reference£º
Patent; Ting, Pauline C.; Aslanian, Robert; Caplen, Mary Ann; Cao, Jianhua; Chan, Tin-Yau; Kim, David; Kim, Hyunjin; Kim, Jae-Hun; Kuang, Rongze; Lee, Joe F.; Schwerdt, John; Wu, Heping; Zorn, Nicolas; US2011/224137; (2011); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica