Zheng, Sheng; Zhang, Ying; Chen, Shujie; Zhang, Zeyu; Chen, Fei; Zhang, Zizhen; Hu, Zhenhua; Tian, Jie; Wang, Liangjing published the artcile< A preliminary study of dual-band confocal laser endomicroscopy combined with image mosaic in the diagnosis of liver cancer>, Application In Synthesis of 2591-17-5, the main research area is diagnosis liver cancer confocal laser endomicroscopy; Confocal laser endomicroscopy; Fluorescein sodium; Image mosaic; Indocyanine green; Primary liver cancer; Tumor margin.
Accurate identification of tumor tissues and their margins are still challenging for conventional clin. imaging methods during liver cancer surgery. In this study, dual-band confocal laser endomicroscopy (CLE) combined with image mosaic was used to guide liver cancer surgery. In the experiments with mice bearing orthotropic liver tumor, CLE can accurately detect the tumors and identify their margins with two excitation wavelengths of 488 nm and 660 nm by clin. available dyes fluorescein sodium (FS) or indocyanine green (ICG). The mosaic CLE images enlarged the imaging field and detected the liver tumor margins more accurately. Normal liver tissues fluorescence intensity of CLE images was significantly higher than that of tumor tissues in the same tumor-bearing mice (P < 0.0001). Overall, dual-band CLE imaging demonstrates to be a promising method to identify liver tumor tissues and margins, which has the prospect of clin. application and helps to achieve intraoperative radical resection. Nanomedicine (New York, NY, United States) published new progress about Anesthesia. 2591-17-5 belongs to class thiazole, and the molecular formula is C11H8N2O3S2, Application In Synthesis of 2591-17-5.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica