Saito-Moriya, Ryohei; Nakayama, Jun; Kamiya, Genta; Nobuo Kitada; Obata, Rika; Maki, Shojiro A.; Aoyama, Hiroshi published the artcile< How to select firefly luciferin analogues for in vivo imaging>, Application of C11H8N2O3S2, the main research area is review bioluminescence firefly luciferin analog imaging; bioluminescence imaging; high sensitivity; luciferase; luciferin analogue; multicolor; near-infrared light.
A review. Bioluminescence reactions are widely applied in optical in vivo imaging in the life science and medical fields. Such reactions produce light upon the oxidation of a luciferin (substrate) catalyzed by a luciferase (enzyme), and this bioluminescence enables the quantification of tumor cells and gene expression in animal models. Many researchers have developed single-color or multicolor bioluminescence systems based on artificial luciferin analogs and/or luciferase mutants, for application in vivo bioluminescence imaging (BLI). In the current review, we focus on the characteristics of firefly BLI technol. and discuss the development of luciferin analogs for high-resolution in vivo BLI. In addition, we discuss the novel luciferin analogs TokeOni and seMpai, which show potential as high-sensitivity in vivo BLI reagents.
International Journal of Molecular Sciences published new progress about Bioluminescent imaging. 2591-17-5 belongs to class thiazole, and the molecular formula is C11H8N2O3S2, Application of C11H8N2O3S2.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica