Masuda, Naoyuki; Yamamoto, Osamu; Fujii, Masahiro; Ohgami, Tetsuro; Moritomo, Ayako; Kontani, Toru; Kageyama, Shunji; Ohta, Mitsuaki published the artcile< Regioselective Alkylation of Thiazolylsulfonamides: Direct and Efficient Synthesis of 3-Alkylthiazolidene Derivatives>, Recommanded Product: 5-Isopropylthiazol-2-amine, the main research area is thiazolylsulfonamide alkyl halide regioselective alkylation; thiazolidene sulfonamide preparation; alkylthiazolidene sulfonamide preparation; sulfonyliminothiazole preparation.
Various N(3)-alkylated thiazolidene sulfonamide derivatives were efficiently prepared by the direct endo-selective alkylation of thiazolyl sulfonamides. The effects of different bases and solvents were investigated, and the NaH-THF combination was found to be the most effective at conferring high yields and endo-selectivity.
Synthetic Communications published new progress about Alkylation, regioselective. 101080-15-3 belongs to class thiazole, and the molecular formula is C6H10N2S, Recommanded Product: 5-Isopropylthiazol-2-amine.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica