7305-71-7, 2-Amino-5-methylthiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a stirred solution of -corresponding hetero amines a?e (0.04?mol) and triethyl amine (0.04?mol) in chloroform (200?ml) was added drop wise chloroacetyl chloride (0.04?mol) at 0?5?¡ãC. After addition, the resulting mixture was stirred overnight at room temperature. Reaction completion was monitored through thin layer chromatography using hexane:ethyl acetate (8:2) as mobile phase. The reaction mixture was concentrated to get solid and as such taken in the methanol solution. The precipitates thus separated out were allowed to stand 2?h. The resultant solid 1a?e was filtered, washed, dried and as such taken for the next step.
As the paragraph descriping shows that 7305-71-7 is playing an increasingly important role.
Reference£º
Article; Patel, Navin B.; Purohit, Amit C.; Rajani, Dhanji P.; Moo-Puc, Rosa; Rivera, Gildardo; European Journal of Medicinal Chemistry; vol. 62; (2013); p. 677 – 687;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica